What is CBD and how it is apart of the human body.
The human body produces certain cannabinoids on its own, as illness, age and other factors can cause our bodies not produce enough CBD and creates a deficiency. When our bodies are low on CBD it affects our endocannabinoid system and puts our bodies out of balance. Examples are feeling more pain in the body, not getting the proper sleep, creating anxiety issues, and much more. Shown above is a diagram which shows the systems CBD helps in and are categorized as CB1 and CB2 receptors. CBD is a natural supplement that our bodies need just vitamin C, D etc, but CBD is a much needed supplement compared to other vitamins and plays a much bigger role in overall wellbeing, as studies show.
People who are taking CBD have reported a great number of benefits in treating a number of symptoms including ailments that have, until recently, been treatable only with prescription drugs or synthetic cannabinoids. Cancer patients suffering from pain and nausea from chemotherapy, Alzheimer’s, seizures caused by Epilepsy, Multiple Sclerosis, Anxiety, and Depression are just a few of the notable ones. CBD’s benefits have been studied and documented extensively and the number of patients reporting improvement of their systems is growing, so what is Cannabidiol and
How does it work?
Cannabidiol, as the name suggests, is a cannabinoid. Most cannabinoids come from plants like the Hemp or cannabis. There are currently 3 categories of cannabinoids and it is important to understand what they are, if we are going to also understand how they work together. Phytocannabinoids are cannabinoids that are produced in plants. As mentioned above, plants like the Hemp or cannabis plant and cacao plant are the most notable. Synthetic cannabinoids, are cannabinoids produced in a lab setting, by pharmaceutical companies and Endocannabinoids are produced inside your body and work with the Endocannabinoid System. Although the discovery of the Endocannabinoid System is relatively new, it was named after phytocannabinoids from the cannabis plant. In 1964, researches stumbles on CBD and then THC and then, “On July 18, 1990, at a meeting of the National Academy of Science’s Institute of Medicine, Lisa Matsuda announced that she and her colleagues at the National Institute of Mental Health (NIMH) had achieved a major breakthrough — they had pinpointed the exact DNA sequence that encodes a THC-sensitive receptor in the rat’s brain.”1 From there, further research was able to discover the two Endocannabinoids that act as neurotransmitters for the system, anandamide and 2 AG. Then the breakthrough that changed cannabinoid research, the discovery that the same receptors that exist in rats also exist in almost every living animal on the planet, including humans. “By using a plant that has been around for thousands of years, we discovered a new physiological system of immense importance,” says Raphael Mechoulam, the dean of the transnational cannabinoid research community. “We wouldn’t have been able to get there if we had not looked at the plant.”2 When we look at CBD’s effects on the Endocannabinoid System, it is important to understand that anandamide and 2 AG are neurotransmitters that carry signals between receptor ends. One of CBD’s benefits is it’s ability to act as a modulator at the receptor itself. Cannabinoids strive to maintain a physiological balance and influence the system either negatively and positively, to achieve homeostasis. This means that if the receptors are inflamed and overactive, the cannabinoids try to calm the receptor and reduce inflammation. CBD, in particular, can also alter the life span of anandamide and 2 AG, leading to over production of cannabinoids and allowing them to work better. As well it has the ability to penetrate the cell walls of the receptors and influence the rate of neurotransmitter release. This is very simplified view of the Endocannabinoid System and how it works but it does give us a glance into the value of CBD to our ECS.