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Benefits Of CBD


Cannabidiol (CBD) is becoming one of the most talked about aspects of the cannabis industry, and for good reason. People who are taking CBD have reported a great number of benefits in treating a number of symptoms including ailments that have, until recently, been treatable only with prescription drugs or synthetic cannabinoids. Cancer patients suffering from pain and nausea from chemotherapy, Alzheimer’s, seizures caused by Epilepsy, Multiple Sclerosis, Anxiety, and Depression are just a few of the notable ones. CBD’s benefits have been studied and documented extensively and the number of patients reporting improvement of their systems is growing, so what is Cannabidiol and how does it work?


Cannabidiol, as the name suggests, is a cannabinoid. Most cannabinoids come from plants like the cannabis plant but there are others that produce them as well. There are currently 3 categories of cannabinoids and it is important to understand what they are, if we are going to also understand how they work together. Phytocannabinoids are cannabinoids that are produced in plants. As mentioned above, plants like the cannabis plant and cacao plant are the most notable. Synthetic cannabinoids, are cannabinoids produced in a lab setting, by pharmaceutical companies and Endocannabinoids are produced inside your body and work with the Endocannabinoid System. Although the discovery of the Endocannabinoid System is relatively new, it was named after phytocannabinoids from the cannabis plant. In 1964, researches stumbles on CBD and then THC and then, “On July 18, 1990, at a meeting of the National Academy of Science’s Institute of Medicine, Lisa Matsuda announced that she and her colleagues at the National Institute of Mental Health (NIMH) had achieved a major breakthrough — they had pinpointed the exact DNA sequence that encodes a THC-sensitive receptor in the rat’s brain.”1 From there, further research was able to discover the two Endocannabinoids that act as neurotransmitters for the system, anandamide and 2 AG. Then the breakthrough that changed cannabinoid research, the discovery that the same receptors that exist in rats also exist in almost every living animal on the planet, including humans. “By using a plant that has been around for thousands of years, we dis- covered a new physiological system of immense importance,” says Raphael Mechoulam, the dean of the transnational cannabinoid research community. “We wouldn’t have been able to get there if we had not looked at the plant.”2 When we look at CBD’s effects on the Endocannabinoid System, it is important to understand that anandamide and 2 AG are neurotransmitters that carry signals between receptor ends. One of CBD’s benefits is it’s ability to act as a modulator at the receptor itself. Cannabinoids strive to maintain a physiological balance and influence the system either negatively and positively, to achieve homeostasis. This means that if the receptors are inflamed and overactive, the cannabinoids try to calm the receptor and reduce inflammation. CBD, in particular, can also alter the life span of anandamide and 2 AG, leading to over production of cannabinoids and allowing them to work better. As well it has the ability to penetrate the cell walls of the receptors and influence the rate of neurotransmitter release. This is very simplified view of the Endocannabinoid System and how it works but it does give us a glance into the value of CBD to our ECS.


To get maximum benefit from CBD, you need to identify the sight of the symptom and use the delivery system that makes the most sense. CBD topicals are of great benefit to people suffering localized joint and muscle pain, because the CBD is able to penetrate the tissue directly at the site of the injury or symptom. People with psoriasis, eczema, pain, inflammation, arthritis, neuropathy, and fibromyalgia see benefits from CBD lotions, salves, and balms. The sublingual CBD delivery system most commonly used with the most benefits for people suffering from anxiety, depression, chronic pain, inflammation, nausea, side effects of Cancer treatment, Alzheimer’s, and other neurological disorders, is what is known as Full Spectrum CBD Tincture. Some CBD tinctures are suspended in products that come with amazing benefits of their own including non gmo organic Hemp Oil and Medium-Chain Triglyceride Oil, aka MCT Oil. MCT has been classified as a Superfood in it’s own right and has been shown to help with weight maintenance, it’s ability to lower blood sugar, increase nutrient absorption, improve athletic performance, and is a natural anti-convulsant. When combined with CBD, these benefits are increased.


Dosing of CBD can also influences its benefits and is currently one of the least understood aspects of taking CBD. Part of the problem lies in the bioavailability of certain products, which is the measure of the amount of CBD, or other medication, that reaches our blood stream. Taking any supplement orally, subjects it to digestive enzymes and fluids that start to break down the medication, before it can reach the blood stream. Taking CBD tablets and capsules, although they have benefits, don’t produce the full amount of CBD you are taking. Taking CBD tincture or vaping CBD are proven to be the best delivery methods, getting CBD directly into the blood stream. Vaping delivers CBD faster than sublingual (under the tongue) application but it’s benefits have been proven to fade faster than CBD oil topicals or tincture. At this point, the only delivery systems that are more effective than straight injection are sublingually applied tincture or topically applied to skin. Dosing depends a lot on the weight of the person taking CBD, as well as the ailment that you are taking it for. Another variable is CBD’s affinity to bind to other receptors in the body, beyond just the endocannabinoid System. In smaller doses, CBD will centre it’s effects on the CB1 and CB2 receptors in the ECS, however, it will bind to others, adding to its effectiveness overall. So, not taking too much and taking too little can hinder the effects that CBD has on your system. Just remember that you cannot overdose on CBD. Always consult a physician before taking any CBD or Dietary supplements etc before use. 


 What is Hemp?


Hemp is a powerful plant, and a powerfully misunderstood one. Many people confuse hemp with marijuana, and while they hail from the same plant—cannabis—they’re very different from each other.

In fact, hemp has a wide range of commercial applications, as a component in building materials to clothing and textiles. It’s also the source of CBD oil, which has gained recent popularity thanks to its potential for relieving conditions like arthritis pain, anxiety, and severe epilepsy.


How Safe Is CBD?


First, let’s ease any concerns you have about CBD. The good news is that CBD has been shown to be safe for humans, even in chronic doses as high as 1,500 mg per day.

Not only is CBD safe, but it produces very few side effects, which is why it’s become so popular. Experiencing any side effects at all with CBD is rare, but if you do, they might include:

  • Tiredness
  • Diarrhea
  • Nausea
  • Changes in appetite or weight
  • Dry mouth
  • Low blood pressure

Of these side effects, tiredness is the most common. As we said, for most people, experiencing side effects with CBD is rare.

However, there are a few groups of people who should avoid using CBD:

  1. Pregnant or breastfeeding women should avoid CBD. Not enough studies of CBD have been conducted in this group to determine if it’s safe or not for them to use. Until then, it’s best to be safe and avoid using CBD.
  2. People taking other medication may also want to avoid CBD. They tend to be the people most likely to experience side effects, due to the interaction between the CBD and the drug they’re taking. If you are taking other medications, speak with your doctor first before taking CBD. They can advise you of any adverse reactions you could experience, based on their knowledge of your medical history.
  3. Finally, as with pregnant women, not enough studies have been performed on the safety of CBD in children. One notable exception here is in cases of pediatric epilepsy.  Both the FDA-approved drug Epidiolex (which contains CBD), and other forms of medical CBD have been shown to help treat severe epilepsy. If you want to give CBD to your child, it’s best to speak first with your pediatrician to ensure it will be safe for them to use.

ou must always consult you phscian before taking CBD oil.

 

How Much CBD Should I Take?


The Right CBD dose for you can depend on a few factors,including your weight, any other conditions you may have, medication you are taking. It also depends on your personal body chemistry and sensitivity to CBD.

When determining your ideal CBD dosage, your goal is to find the lowest dose that provides the benefits you need with few or no side effects.

Using the dosage chart below, start with the lowest recommended dose for your body weight, and gradually increase from there until you feel the desired effects. Once you’ve found that dose, you can stick with it. Studies show that people do not develop a tolerance to CBD the way they do with other cannabis products like marijuana.


How long does it take to feel the effects of CBD oil? 


How long you’ll have to wait to feel the CBD, as well as how long it will last, depends on which administration method you choose.

  • CBD products taken orally, such as edibles, powders, or capsules, tend to have longer-lasting effects, but onset takes longer, too. Before it can enter your bloodstream, where it begins to interact with your endocannabinoid system, it has to go through your digestive system first (which can take 30 to 90 minutes).
  • CBD oil administered sublingually has a much faster onset, because it bypasses the digestive system and enters your bloodstream directly under the tongue. Users start to feel effects within 5 to 20 minutes.
  • CBD extracts inhaled with a vape pen provide the quickest effects, making them ideal for acute symptoms. After inhalation, users start to feel the effects within a few minutes. However, effects only last for a few hours.
  • CBD oils applied topically, such as lotions or balms, are best for treating targeted areas. The oil can be massaged directly onto the area to relieve pain or inflammation within minutes. Effects can last for several hours.  

Not only does the method of administration affect the onset and duration of effects, but it can also affect the size of the dose you need to take. CBD has very low oral bioavailability, so CBD products ingested orally will lose a significant amount of the CBD through the digestive system, leaving only a fraction of it to make it into the bloodstream and exert the desired effects.

When applied topically to the skin, CBD also won’t reach the bloodstream. Instead, it will interact with nearby cannabinoid receptors to treat the pain. Similar to oral ingestion, transdermal application typically requires a higher dose, in order to ensure it permeates the skin deep enough to reach those cannabinoid receptors.

Because the other two methods (sublingual and inhalation) allow the CBD to enter the bloodstream directly, a higher amount of the CBD is absorbed into your system. As a result, you can take a lower dose of CBD when you use sublingual tinctures or vape extracts.

Here’s an overview of the different CBD ingestion methods and how they can affect your system.

   


 

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